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Converging Pathways of Pain Research at NIDCR

Introduction

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Pain - Beginnings of Pain Research at NIDCR - This page
  - and the Dentist
  - Pain Ron Dubner and the "Lone Rangers"
Pain - A New Multi-Disciplinary Unit
Pain - Behavioral & Neural Responses to Pain
  - The Monkey's Informed Choices
  - Findings from the Behaving Monkey Studies
Pain - Testing Old and New Drugs for Pain
  - Differential Measurement of Pain Perception
  - Testing Old and New Drugs for Pain
Pain - A Laboratory Model For Clinical Pain
Pain - The Biochemistry & Genetics of Pain
  - Mapping the Spinal Cord
  - The Dynorphin Connection
  - Future Directions
Pain - Epilogue
Pain - Exhibit Index

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Introduction

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Pain is a universally known and feared human condition, yet surely it is one of the least understood. Within this century it has been a philosophic problem, an enigma of neurophysiology, a psychological puzzle, a challenge to anesthesiologists, oncologists, nurses, clinicians of all kinds; and much of what we now think we know about pain still seems contradictory and paradoxical.

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Here is another puzzle: how did the most versatile and productive pain research unit at NIH establish itself in the National Institute of Dental Research?

Pain and the Dentist

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The story begins in the late 1950s in the dentist's office. The mass screenings of the World Wars had revealed the failure of many Americans to seek regular dental care and the disastrous consequences that followed. The American Dental Association, the National Institute of Dental Research (NIDR; renamed the National Institute of Dental and Craniofacial Research (NIDCR) in 1999), and other authorities actively promoted regular dental visits, especially for children. But increased numbers of visits only pointed to the underlying problem: many Americans associated dentistry with pain and faced each appointment with dread.
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  Photograph of Edward DriscollEdward Driscoll

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