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Dr. Herald R. Cox joined RML to find a simple method to produce vaccines and perfected the method of using chicken embryos (eggs), publishing on this in 1938. One bacteriologist and two technicians could now prepare 40 to 50 liters of vaccine a week. The technique was also useful in producing other vaccines and is still used for some vaccines. After Cox’s innovation, the cost per dose of RMSF vaccine went from $20 to $1.

1937     1937

MARCH 28:  The Washington Star published “Tick is Conquered,” Lucy Salamanca, describing in some detail the work on RMSF and Spencer and Parker’s development of the vaccine.
L. Salamanca. "Tick is Conquered: Scientific G-Men Perfect Vaccine Against Rocky Mountain Scourge After Six Experimenters Lose Lives." Washington, D.C. Sunday Star, March 28, 1937.  Download the transcript. (75 kB)

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