The illustration, on the right, shows the basic structure of immunoglobulins. Molecules in the heavy chains weigh more than those in the light chains. The amino acids in the constant regions do not change, while those in the variable region usually do change. Potter asked how this structure affects how immunoglobulins protect the body.
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Based on an illustration from the University of Arizona
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This 1976 photograph shows how Potter augmented his glasses with the addition of magnifying lenses that allowed him to see small details. It is perhaps the best visual metaphor for his careful and precise research.
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Michael P. Cancro, Ph.D., University of Pennsylvania