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  U.S. Department of Health and Human Services | National Institutes of Health

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Carolyn Hardegree was born in 1933 in Wichita Falls, Texas. She received her M.D. from the University of Texas and is board certified in pediatrics and a fellow of the American Academy of Pediatrics.

Dr. Hardegree’s research was in bacterial toxins and vaccines. She worked with Dr. Margaret Pittman and Dr. Michael Barile on tetanus toxoids studies in humans and guinea pigs. She published the article “Immunization Against Neonatal Tetanus in New Guinea” in 1970 (linked below in publications).

Dr. Hardegree worked in the National Institutes of Health (NIH) Division of Biologics Standards (DBS) Laboratory of Bacterial Products and became Chief of the Section on Bacterial Toxins in 1969.

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Newspaper wedding announcement with photo of Dr. M. Carolyn Hardegree

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Carolyn Hardegree's portrait from her wedding announcement in The (from the San Angelo Weekly Standard newspaper.

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The San Angelo Weekly Standard (Texas)[Texas], Friday, October 6, 1961). 

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FDA History Office 

In 1985, she was Director of the Division of Bacterial Products and worked in Building 29, Room 122A. By 1990, she was the Director of the Office of Vaccine Research and Review at the Food and Drug Administration’s (FDA) Center for Biologics Evaluation and Research (CBER) where she worked in Building 29B, Room 1H16. In 1995, Dr. Hardegree was the Director of the Office of Biologics Research and she returned to working in Building 29, Room 122A. She retired in 1999 as the Director of the Office of Vaccines Research and Review at CBER.

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