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She joined the NIH Division of Biologics Control (later the Division of Biologics Standards [DBS]) in 1936, with her mentor Dr. Sara E. Branham; they were both part of a group of women bacteriologists who studied at University of Chicago. They worked to develop standards for the meningococcal antiserum.

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During World War II, Dr. Pittman investigated the safety of blood and blood products, discovering and eliminating the cause of fever and death from plasma infusions.

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In 1944, she developed a new assay to test the potency of the pertussis vaccine, under the direction of Dr. Milton Veldee, Director of the Biologics Control Laboratory at the time.

After World War II, Dr. Pittman continued to work with other bacterial vaccines, including cholera, where she worked with the Southeast Asia Treaty Organization (SEATO). She was also instrumental in assessing the efficacy of and establish national and international standards for the production of the yellow fever vaccine and the typhoid vaccine. 

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Dr Pittman handles a mouse in a laboratory as another lab member observesImage Added

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Dr. Pittman working in the lab

After her 1971 retirement, she continued as a guest worker in her office (Building 29, Fourth Floor) until 1993. Co-workers said that she "slowed down to working only 40 hours a week" after retiring

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Dr. Pittman worked in Building 29, Fourth Floor from 1960 to 1971.

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