The Molecular Basis of Evolution
This illustration from the book was marked up by Dr Anfinsen.
The Basis of Evolution was published by Christian Anfinsen in 1959.
And finally, Anfinsen tied protein chemistry, genetics, and evolution together. He wrote, “The principle aim of this book has been to examine the basic principles underlying another possible method for the study of evolution (instead of fossils or comparative anatomy). This method is based on the hypothesis that the individual proteins which characterize a particular species are a unique reflection of the genes which control their synthesis….The structure of proteins may be a relatively direct expression of gene structure and…comparative protein chemistry may furnish a qualitative view of genotypic differences and similarities.”
How thrilled Anfinsen would be to know that researchers are now using protein chemistry and genetics in their study of the evolution of various organisms and even of human migration.
You can download and read The Molecular Basis of Evolution through NLM KKBBLS.pdf pdf (18.2mb)
The Basis of Evolution was published by Christian Anfinsen in 1959.
Additional Images
Figure 2. Relationships of the phyla of the animal kingdom. The arrangement here is based on the scheme given by L. H. Hyman in The Invertebrates volume 1, McGraw-Hill Book Company, p. 38, 1940.
The evolution of the horses. The diagram shows the geographic distribution of the various forms and indicates their manner of securing food by browsing or by grazing. Redrawn from G. G. Simpson, Horses, 1951, by permission of Oxford University Press.
Figure 11. Mitotic cell division in the common onion: A, interphase; B, prophase; C, metaphase; D anaphase; E telophase; F daughter cells. From T. Dobzhansky, Evolution, Genetics, and Man, John Wiley & Sons, 1955.