NIH Eminent Scientist Profiles

Roscoe Brady, M.D., was the world's leading researcher on hereditary metabolic storage diseases, also called lipid or lysosomal storage disorders, such as Gaucher, Niemann-Pick, Fabry and Tay-Sachs. His NIH laboratory defined much of what is known of their biochemistry, enzymatic bases and metabolic defects. Dr. Brady was the recipient of the Canada Gairdner Award (1973), Lasker Award (1982), and the National Medal of Technology and Innovation (2008), and he was elected to the National Academy of Sciences in 1983 and the National Academy of Medicine in 1985.

The Office of NIH History and Stetten Museum has gathered the following growing list of resources concerning Dr. Brady:

Dr. Brady's Own Reflections
• Reflection essay for Journal of Biological Chemistry, 2010: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3009847
• Essay on hereditary diseases for Angewandte Chemie International Edition, 1973: http://onlinelibrary.wiley.com/doi/10.1002/anie.197300011/abstract

NIH Publications
• Biography on Brady in online exhibit, 2016: https://history.nih.gov/exhibits/gaucher/docs/page_05.html
• Announcement of National Medal of Technology and Innovation award in NIH Record, 2008: https://nihrecord.nih.gov/newsletters/2008/10_31_2008/story5.htm
• Honoring 50 years in NIH Record, 2002: https://nihrecord.nih.gov/newsletters/12_10_2002/story06.htm

Journal Publications
• Tribute by Nicole Kresge, Robert D. Simoni, in Journal of Biological Chemistry, 2005: http://www.jbc.org/content/280/48/e45.full.pdf

Non-journal Publications
• Obituary in Washington Post, 2016: http://www.legacy.com/obituaries/washingtonpost/obituary.aspx?n=roscoe-o-brady&pid=180345809
• Biography in National Institute of Neurological Disorders and Strokes, 2014: https://neuroscience.nih.gov/ninds/Faculty/Profile/roscoe-brady.aspx
• Announcement of drug use in Washington Post, 1991: https://www.washingtonpost.com/archive/lifestyle/wellness/1991/06/25/the-high-cost-of-rare-diseases-when-patients-cant-afford-to-buy-lifesaving-drugs/6876b65b-886d-4585-b162-fe4b1296f2a5/.
• Explanation for Lasker Award, 1982: http://www.laskerfoundation.org/awards/show/lysosomal-storage-diseases