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Download the PDF:  Strich_Jeffery_oral_history_2020  (87 KB)

Read a paper: see the list at the end of the interview.

Read "Real-world Inpatient Use of Medications Repurposed for COVID-19 in U.S. Hospitals, March-May 2020"

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A great example of that is two of our patients early on were put on mechanical ventilation early in their disease course because people commented about how quickly these patients becomecritically become critically ill and need mechanical ventilation.  That’s what people were doing and people didn’t want to wait till they got too sick to put them on mechanical ventilation. Now we have currently a patient in our ICU that probably back in March would have been intubated based on his clinical scenario and how much oxygen he is on, but we’ve learned—we’re using other non-invasive ways of managing his oxygenation, including having him lay on his stomach to increase his oxygenation without having to go on a breathing machine. This allowed him not to be mechanically ventilated. We’ve learned a lot about this from where we are now in October versus where we were back in March.

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Barr: It’s true people often don't realize all the work that goes behind all these clinical trials. Well, thank you very much and I wish you the best of luck on your research and, of course, thank you for caring for all these patients.

Strich: You’re welcome.

Read a paper:
Real-World Inpatient Use of Medications Repurposed for Coronavirus Disease 2019 in United States Hospitals, March–May 2020, Open Forum Infect Dis., 2021 Feb; 8(2): ofaa616. Published online 2020 Dec 15. doi: 10.1093/ofid/ofaa616.

Sensitivity in Detection of Antibodies to Nucleocapsid and Spike Proteins of Severe Acute Respiratory Syndrome Coronavirus 2 in Patients With Coronavirus Disease 2019, J Infect Dis, 2020 Jun 29; 222(2): 206-213.  doi: 10.1093/infdis/jiaa273.

Fostamatinib Inhibits Neutrophils Extracellular Traps Induced by COVID-19 Patient Plasma: A Potential Therapeutic, J Infect Dis, 2021 Mar 29; 223(6): 981-984.   doi: 10.1093/infdis/jiaa789.

Association Between Caseload Surge and COVID-19 Survival in 558 U.S. Hospitals, March to August 2020, Ann Intern Med, 2021 Sep; 174(9): 1240-1251.  doi: 10.7326/M21-1213. Epub 2021 Jul 6.

High-throughput, single-copy sequencing reveals SARS-CoV-2 spike variants coincident with mounting humoral immunity during acute COVID-19, PLoS Pathog., 2021 Apr 8; 17(4): e1009431.  doi: 10.1371/journal.ppat.1009431. eCollection 2021 Apr.