Versions Compared

Key

  • This line was added.
  • This line was removed.
  • Formatting was changed.

...

Caption

Donated by Dr. Christian Anfinsen


Dr. David R. Davies graduated from Oxford University in 1949 and received a Ph.D. in 1952. In 1955, he joined NIMH and moved to NIDDK six years later. His research used x-ray crystallography to determine the three-dimensional structure of proteins and nucleic acids.

Read our oral histories with David Davies


Additional Images


Image Added

Caption

Staphylococcal Nuclease

|

This is a model of staphylococcal nuclease built by NIH scientists Drs. Christian B. Anfinsen and David R. Davies for use in their evening seminars for Research Associates. Models such as this were used for teaching purposes in the 1960s and 1970s, though they have since been supplanted by computer graphics. The plastic tube in this molecular model represents the polypeptide backbone and the amino acid side chains are shown by small metal rods which represent molecular bonds.

Dr. Davies is known for his analysis of the 3-dimensional structures of molecules, and Dr. Anfinsen received a 1972 Nobel Prize for his theory that the pattern of protein folding is determined by its amino acid sequence. In their teaching, both continued NIH's tradition of actively mentoring future research scientists.


Image Added


Image Added


Image Added


Image Added


Image Added


Image Added


3d models such as this have largely been supplanted by 3d graphics and resources such as the RCSB Protein Data Bank website: Staphylococcal Nuclease interactive graphic.

...


Button
linkAnfinsen - Artifacts Home
pageArtifacts
aligncenter
Image Removed