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Human Genetics and Medical Research

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Cracking the genetic code allowed us to study diseases at the molecular level, which has increased our knowledge of potential preventions and treatments for diseases. The study of genetics has become central to the science of medicine. This exhibit asks many questions: How do genes cause disease? Can gene therapy work? How do we manipulate genes and should we?
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Martin Rodbell

: How Cells Respond to Signals

Rodbell sitting in a boat holding a cameraMartin Rodbell and his colleagues discovered a mechanism that transformed our understanding of how cells respond to signals. In a series of pioneering experiments conducted at the NIH, Rodbell studied hormones--substances which have specific effects on cells' activity. He won the 1994 Nobel Prize for this work.

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The AMINCO-Bowman Spectrophotofluorometer

Dr Bowman
In the 1950s, the NIH's Dr. Robert Bowman developed a sensitive instrument called the spectrophotofluorometer, or “SPF”, that allowed scientists to use fluorescence as a way to identify and measure tiny amounts of substances in the body.  This exhibit explores the instrument and its use in scientific studies ranging from anti-depressant medication to AIDS research and the Human Genome Project.

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Scientific and Biomedical Instruments and other "Things"

width-one-thirdConverging Pathways of Pain Research at NIDCRImage Removed
The story of how pain research evolved at NIDCR.-grid
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Image RemovedJoseph Goldberger & the War on Pellagra
Public Health Service physician Dr. Joseph Goldberger's discovery of the cause of pellagra, a disease, resulting from a diet deficient in vitamin B, that killed many poor Southerners in the early part of the 20th century.
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A History of the Pregnancy Test KitImage Removed

A History of the Pregnancy Test Kit

Woman holding a pregnancy testImage Added
This looks at the history of the home pregnancy test and examines its place in our culture. Research that led to a sensitive, accurate pregnancy test was done by scientists in the Reproductive Research Branch of the National Institute of Child Health and Human Development at the National Institutes of Health.

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The AMINCO-Bowman Spectrophotofluorometer

Dr BowmanImage Added
In the 1950s, the NIH's Dr. Robert Bowman developed a sensitive instrument called the spectrophotofluorometer, or “SPF”, that allowed scientists to use fluorescence as a way to identify and measure tiny amounts of substances in the body.  This exhibit explores the instrument and its use in scientific studies ranging from anti-depressant medication to AIDS research and the Human Genome Project.

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Innovation and Invention: NIH and Prosthetic Heart Valves

Prosthetic Heart ExhibitImage Added
The development of artificial heart valves involved surgeons, engineers, patients, and regulators.  This exhibit explores their stories and presents current and future examples of artificial heart valve innovation. The exhibit is currently in the process of moving from the NIH to the FDA and is expected to be on display again by 2020. The virtual exhibit is under construction and the physical exhibit is currently on display at the FDA.

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Cray X-MP/22 Computer

NIH's first supercomputer, the Cray X-MP/22, was the world's fastest supercomputer from 1983-1986, and the first one devoted solely to biomedical research.  Both the physical and virtual exhibits are under development, but you can still see the Cray at its exhibit site by visiting the real thing [this would be a link to the map page]

Image RemovedMartin Rodbell: How Cells Respond to Signals
This exhibit explains the work of Martin Rodbell and his colleagues in discovering a mechanism that transformed our understanding of how cells respond to signals. In a series of pioneering experiments conducted at the NIH, Rodbell studied hormones--substances which have specific effects on cells' activity. He could not have predicted the broad impact his findings would have

.

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Siemens 1-A Electron Microscope

This Siemens 1-A Electron Microscope was used for over three decades by Dr. Albert Kapikian, NIAID.  The instrument was used to detect and characterize various viruses.  While the virtual exhibit is being constructed, you can Visit the real thing [this would be a link to the map page]

Synthetic Opiates and OpioidsImage RemovedSynthetic Opiates and Opioids
The quest for new painkillers and a synthetic source for morphine and codeine

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Human Genetics and Medical Research — Cracking the genetic code allowed us to study diseases at the molecular level, which has increased our knowledge of potential preventions and treatments for diseases. The study of genetics has become central to the science of medicine. This exhibit asks many questions: How do genes cause disease? Can gene therapy work? How do we manipulate genes and should we?
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Objects

Varian A-60 NMR

A Varian A-60 NMR (Nuclear Magnetic Resonance) was used at NIH in the 1960s to identify molecular structures and their reactions in relation to biomedical research.  The virtual exhibit is under construction, but visit the real thing [this would be a link to the map page].

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Early Computing at NIH

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This snapshot of some of the computing tools used in NIH labs highlights objects that are now in the NIH Stetten Museum collection.

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Early Medical Instruments at the NIH

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A cross section of precision instruments used at NIH between 1945 and 1965 is presented.

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Equal Arm Analytical BalancesImage Removed

Equal Arm Analytical Balances

Instruments,

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This type of balance is designed on a “seesaw” principle

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to measure mass precisely by placing a sample in one pan and a known weight in an opposing pan until an equilibrium was established.

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Laboratory Instrument Computer (LINC)

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The story of one of the first supercomputers from its conception in MIT's Lincoln Laboratory, through its use in biomedical research laboratories.

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Medical PostersImage Removed

Medical Posters

Early Stage Breast Cancer PosterImage Added
A collection of 24 medical posters drawn by artists at the NIH, representing topics from arthritis to women's health.

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The National Cancer Institute Real-Time Picture Processor

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The Real Time Picture Processor (RTPP) was one of the first special-purpose hardware computers developed for grayscale image processing and was designed to aid in biological image analysis.

Institutes and Ideas


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Converging Pathways of Pain Research at NIDCR

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The story of how pain research evolved at NIDCR.

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Human Genetics and Medical Research

Image Added
Cracking the genetic code allowed us to study diseases at the molecular level, which has increased our knowledge of potential preventions and treatments for diseases. The study of genetics has become central to the science of medicine. This exhibit asks many questions: How do genes cause disease? Can gene therapy work? How do we manipulate genes and should we?

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NIBIB: Improving Health Through Emerging Technologies — This exhibit places some examples of cutting-edge research, funded by the National Institute of Biomedical Imaging and Bioengineering, in historical context.  The virtual exhibit is under construction but you can visit the real thing [this would be a link to the map page].

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Synthetic Opiates and Opioids

Opium FlowersImage Added
The quest to free us from a dependence upon certain flowers by developing a synthetic source for morphine and codeine and the development of new painkillers is described.  This work at NIDDK resulted in the NIH Total Opiate Synthesis method.

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The National Cancer Institute Real-Time Picture Processor

 — The

Real Time Picture ProcessorImage Added
The Real Time Picture Processor (RTPP) was one of the first special-purpose hardware computers developed for grayscale image processing and was designed to aid in biological image analysis.

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A History of the Pregnancy Test Kit

Woman holding a pregnancy testImage Added
This looks at the history of the home pregnancy test and examines its place in our culture. Research that led to a sensitive, accurate pregnancy test was done by scientists in the Reproductive Research Branch of the National Institute of Child Health and Human Development at the National Institutes of Health.

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Innovation and Invention: NIH and Prosthetic Heart Valves — The development of artificial heart valves at NHLBI involved surgeons, engineers, patients, and regulators.  This exhibit explores their stories and presents current and future examples of artificial heart valve innovation. The virtual exhibit is under construction and the physical exhibit is currently on display at the FDA.

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Siemens 1-A Electron Microscope — This Siemens 1-A Electron Microscope was used for over three decades by Dr. Albert Kapikian, NIAID.  The instrument was used to detect and characterize various viruses.  While the virtual exhibit is being constructed, you can Visit the real thing [this would be a link to the map page].

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Charles Darwin

Charles DarwinImage Added
Formally titled “Rewriting the Book of Nature: Charles Darwin and the Rise of Evolutionary Theory,” the exhibit describes the Charles Darwin’s life and the fortunes of the theory of evolution by natural selection.
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