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  U.S. Department of Health and Human Services | National Institutes of Health

Biologics Regulation and ResearchThe People and Work of Buildings 29 & 29A

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Building 29A had a different floor plan and design from Building 29 and most other lab buildings at NIH. Instead of a central corridor, there was an exterior corridor around the entire perimeter of the building and then two smaller cross corridors (Neuberg 2014). Labs faced the interior of the building and were shielded from light, heat, and noise from outdoors. A utility core behind each hallway allowed for this configuration and brought electric, plumbing, gas, etc. to the labs. Air intake towers, located in the median of the parking area in front of the building, provided clean air for the mechanical system, while a high velocity exhaust air system was placed on the roof to ensure dilution and dispersion of laboratory and vivarium exhaust air.

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Utility cores are in blue, cross corridors are in red, and the perimeter corridor is in yellow on Building 29A First Floor Plan. 

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NIH Office of Research Facilities 1964

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The upper three floors have the capacity for specialty Biosafety Level 3 (BSL-3) and/or Curren Current Good Manufacturing Practice regulations (cGMP) facilities for the production and storage of biological products.

When the FDA CBER left the NIH campus in 2014, Building 29B underwent some renovations and has since been used as overflow space for NICHD, NIAID, and NIMHD.

Until 2014, Buildings 29, 29A, and 29B represented the only facilities, not just on the NIH campus but in the entire United States, that have functioned since their construction for the primary purpose of regulating biologics.

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