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Adenovirus(es)
First discovered in human adenoids (an adenoid is a tissue at the back of the throat),
this group of 20-sided viruses causes respiratory and other diseases. Adenoviruses contain
DNA.
Allele(s)
One form of a gene: for example, the gene for eye color has alleles for brown, blue,
black, and green eyes. An allele may be dominant or recessive.
Allergic reaction(s) An over-reaction by the body to substances that usually do not bother the average
person. Reactions include sneezing, itching, runny eyes and nose, rashes, wheezing, and
shock.
Amino acid(s) Compounds that link together to make proteins. Essential amino acids are released in
the intestines when food containing protein is digested -- the body cannot make them.
Non-essential amino acids can be made by the body. Amino acids contain carbon, hydrogen,
oxygen, nitrogen, and sometimes sulfur.
Anemia Results when the blood doesnt have enough red blood cells, hemoglobin, or total
volume. Causes include loss of blood, an iron deficiency (so that not enough blood is
formed), or a bone marrow disfunction where the blood is made. Symptoms include being
tired and bone pain.
Apheresis The process of taking blood, cleansing it or adding
certain substances, and returning the blood to the patient.
Artery(ies) A blood vessel which carries blood rich in oxygen and nutrients from the heart to the
cells in the body.
Bacterium (bacteria) A single-celled microscopic organism. Bacteria live in dirt and water, or in plants and
animals. Some bacteria aid digestion, while others can cause diseases like pneumonia,
diphtheria, and tuberculosis. They can be round, rod-shaped or spiral. Vaccinations help
increase immunity to some of the diseases bacteria carry while antibiotics can fight
others.
Carrier(s) A person who has one recessive gene for a recessive genetic disease. Because the person
has only one recessive gene, s/he does not have the disease, but can pass the disease gene
on to her/his children.
Cell(s) The smallest structural unit of life capable of functioning by itself, a cell has a
membrane which allows some things to pass through. Inside the cell are one or more nuclei
and other cellular parts. Cells contain DNA and make up our bodies.
Cholesterol A steroid alcohol which regulates certain cell functions and helps build cell
membranes.
Chromosome(s) Strands of deoxyribonucleic acid contain all or most of the genes of an individual. The
number of chromosomes is specific to an animal or plant -- humans have 46.
Codon(s) Made of three consecutive nucleotides, codons specify a particular amino acid in a
protein or start or stop proteins from being made.
Cultured Microorganisms (like bacteria or viruses) or tissues from plants and animals which are
grown outside the body in a prepared medium in a laboratory.
Degrade The breakdown of a chemical compound into a less complex compound.
Deoxyribonucleic acid (DNA) The molecular basis for heredity, formed in a double helix and held together by
hydrogen bonds between purine and pyrimidine bases. DNA is found in the cell nucleus.
Diphtheria
A contagious disease caused by a bacteria, which inflames
the heart and nervous system and causes the formation of false membranes,
especially in the throat and air passeages.
DNA marker(s) Segments of DNA known to be linked with inheritable traits or diseases. They may not
cause the condition but always appear with the genes that do. Markers are used to find the
locations of genes on chromosomes.
Dominant One of a pair of alleles that suppresses the expression of the other in heterozygous
(having one dominant and one recessive allele) conditions.
Embolism (Emboli)
A blockage of a blood vessel caused by an abnormal particle -- like an air bubble --
circulating in the blood.
Enzyme(s) A complex protein made by a cell which is a catalyst (something that starts a reaction
or chain of events) for a specific biochemical reaction which does not change the enzyme.
Enzymes control digestion, muscle contraction, and many other functions of metabolism.
Expressed When the trait a gene codes for shows in an organisms phenotype, or body, in a
detectable manner.
Familial When a disease occurs in more people in a family than could be expected by chance
alone, the disease is familial or inherited in that family.
Fetal Relating to or coming from an unborn animal, especially an animal in the later stages
of pre-natal development.
Gene(s) A specific sequence of nucleotides in DNA or RNA, it is the unit of inheritance. A gene
codes for the expression of a trait by specifying the structure of a certain protein.
Usually found on a specific place on a chromosome, genes reproduce exactly during cell
division, and usually occur in pairs, except for those genes on the sex chromosomes X and
Y.
Genome(s) All the genetic information that makes an organism.
Hemoglobin A protein in red blood cells that contains iron and transports oxygen from the lungs to
the rest of the body.
Heterozygous When a gene has one dominant and one recessive allele.
Homozygous When a genes alleles are either both dominate or recessive.
Human growth hormone A protein hormone produced by the pituitary gland that promotes growth, fat
mobilization, and inhibition of glucose utilization.
Inflammation A cellular response to injury or stimulation from physical, chemical or biological
agents. When cells inflame, they turn red, heat up, are painful, and swell to get rid of
noxious agents and damaged tissue.
Inherit To receive a gene from a parent during reproduction; in humans, fetuses inherit half of
their genes from their fathers and half from their mothers.
Insulin A protein hormone made by the pancreas which is necessary for metabolizing
carbohydrates and sugars and which is used in the treatment and control of diabetes.
Liposome(s) A fatty droplet of spherical lipid in suspension in tissue.
Lymphocyte(s) A cell made by stem cells (cells in the bone marrow which make many other kinds of
cells) that goes to the lymphoid tissue in the thymus or bone marrow. They fight
infections and make up a large portion of cells in the blood.
Measles A contagious viral disease marked by a fever and rash on the neck and face. Once
youve had measles, you generally are immune to it.
Melanoma A skin tumor containing dark pigment which may be benign or malignant; when malignant
(or cancerous) it spreads rapidly and widely.
Micropipette(s) A fine-pointed tube used for measuring or dispensing very small amounts -- the fluid is
drawn by suction and kept in by closing the top end of the tube.
Molecule(s) The smallest unit that something can be divided into without changing its properties.
The speed of molecular motion and space between them determine if somethings a
liquid, solid, or gas. Molecules are made of atoms and differ from each other in size,
weight, and structure. Chemical action affects molecules.
Mucus A slippery wet substance secreted to moisten and protect tissues -- the most commonly
known is nasal mucus.
Mumps A contagious viral disease with fever and swelling of the parotid gland and the
salivary glands.
Neurological Having to do with the structure or function of the nervous system, which includes the
brain, spinal cord, nerves, ganglion; and/or having to do with the receptors or organs
that receive and interpret stimulations and send impulses to the brain and affector
organs.
Nucleotide(s) A basic structural unit of RNA and DNA, made of a ribose or deoxyribose sugar and a
purine or pyrinidine base and a phosphate group.
Nucleus (nuclei) The part of the cell which is enclosed in its own membrane within the cell and which
contains the materials to make the chromosomes -- important in reproduction and protein
making.
Organism(s) A living being or individual.
Protein(s) A complex substance made of amino acids and which include many compounds necessary for
life like hormones, enzymes, and immunoglobins. Proteins are found in cells and tissue.
The type of protein depends on the kinds and number of amino acids that make it. Proteins
are used in building cells, cell functions, muscle contraction, digestion, growth, etc.
Receptor(s) A cell or group of cells that responds to various stimuli, or a molecule on the surface
of a cell or in the cell that responds to a certain chemical, molecule, or virus, and then
makes the cell do something in reaction such as produce something, stop making something,
let the stimulating material enter the cell, etc.
Recessive An allele which has little or no effect on the phenotype of an organism when paired
with a more dominant allele; it only has an effect when paired with another recessive
allele.
Recombinant DNA Made by cutting up the DNA of one species (usually a bacterium) and inserting the genes
of another species so that the bacterium produces the protein or hormone of the other
organism.
Retrovirus(es) A virus which contains RNA and which uses its RNA as a template to produce its own DNA
when incorporated into the genes of infected cells.
Thrombosis A blockage of a blood vessel due to a blood clot.
Tissue culture(s) Keeping alive and growing body tissue in the laboratory, outside the organism in a
sterile culture medium.
Trait(s) An inherited characteristic which is found in the phenotype
(the physical appearance) or genotype (the genetic material) of an organism.
Traits include eye color, hair color, the shape of body parts and genetic diseases.
Tumor(s) A mass of tissue with no physiological function that arises from tissue for no obvious
cause; it may be benign or malignant (cancerous).
Tumor-infiltrating lymphocyte(s) A cell isolated from a malignant tumor, cultured with interleukin-2, and injected back
into the patient as a tumor-killing cell that has greater toxicity.
Vein(s)
A blood vessel that returns blood from the body to the heart to pick
up more oxygen.
Virus(es)
A disease-causing agent that is able to live and reproduce only inside
living cells. Viruses cause many infectious diseases.
White blood cell(s) A colorless blood cell (because it doesnt have hemoglobin) that fights invaders
to the body and includes lymphocytes, monocytes, neutrophils, eosinophils, and basophils.
Whooping cough An infectious disease caused by a bacteria that spawns a convulsive cough sometimes
followed by a crowing breath. Also called "pertussis."
X-chromosome(s) One of two kinds of chromosomes which help determine the sex of an organism -- females
have two X-chromosomes, males have one (a Y-chromosome is the other chromosome which helps
determine sex).
X-linked A genetic condition arising when an allele coding for a specific genetic trait or disease is only found on the
X-chromosome. If such an allele is recessive, a female (who has two X- chromosomes)
doesnt get the trait, but a male (who has only one X- chromosome) does. X-linked
traits are carried by mothers and passed to their sons.
Y-chromosome(s) One of two kinds of chromosomes which help determine the sex of an organism -- males
have one Y-chromosome, females have none (an X-chromosome is the other chromosome which
helps determine sex).
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