1955 Dr. Julius Axelrod-Dr.
Brodie's former lab technician-had moved on to
the National Institute of Mental Health (NIMH)
and was working on his own experiments. He began
using the new SPF in his research on what are
now known as neurotransmitters
SPF . . . changed the direction of the whole field
wrote Dr. Axelrod, looking back on his experience.
He used the SPF to trace and measure tiny amounts
of norepinephrine and serotonin in the brain.
These neurotransmitters were present in the body
in such minute amounts that no previously existing
technology could have detected them. This research
led to the development of antidepressant drugs
such as Prozac. In 1970 Dr. Axelrod was awarded
the Nobel Prize in Physiology or Medicine for
his work with neurotransmitters.
Dr. Julius Axelrod, left, with Dr. Robert Bowman