G. Gilman (1941-) attended Yale University, majoring in Biochemistry.
He worked with Earl Sutherland
at Case Western Reserve University, where he worked on cyclic AMP
in the thyroid gland. He developed a simple assay technique for
cyclic AMP while working in Marshall Nirenberg's lab at the National
Institute of General Medical Sciences. He later taught at the University
of Virginia, and then became chair of the Department of Pharmacology
at the University of Texas, Dallas.
In 1980, Gilman and his team purified the transducer
protein, called the G-protein because it reacts with GTP. He
to show that the G-protein was necessary for signal transduction.
For more information, click on www.nobel.se/medicine/laureates/1994/gilman-autobio.html.
The Nobel Foundation